NuGenGENtle and Alchemi [.NET Grid Computing Framework]

Our reasons for converting the open source project GENtle to .Net is to make extensive use of the Alchemi [.NET Grid Computing Framework]. In fact we are modifiing Alchemi as well, in order to work specifically with NuGenGENtle datasets. This will allow for the processing of extremely large datasets across multiple Alchemi processes (machines). This will be especially useful for plasmid maps, restriction and ligation and alignments. As well, the fact that we are combining one of our other projects NuGenTransciber (Scans multiple DNA sequences, e.g. from micro-array experiments, for potential binding sites of regulatory transcription factors.) with NuGenGENtle in order to create a very complete and extensible package. Both supporting grid processing and standalone processing.

I seriously can’t wait to get this humming on our SGI Cluster. Very exciting times ahead!
Anthony Nystrom

4 Responses to “NuGenGENtle and Alchemi [.NET Grid Computing Framework]”

  1. stefan demetz Says:

    Have you ever considered using Digipede (www.digipede.net) ? With that you can use even standard PCs or scale to something like HP Cluster Platform (up to 4096 CPUs) on standard Windows 2003 all in .NET 2.0 at 32 or 64 bit

  2. anthonynystrom Says:

    Never heard of it until now. We will check in to it. Thanks

  3. mattman206 Says:

    @stefan Actually Alchemi runs on any kind of desktop you have laying around — I have a cluster of a bunch of old Pentium IIIs that I’m using Alchemi on. Digipede is so expensive (hundreds of dollars per node) while Alchemi is completely free and has a very similar API.

  4. Anthony Nystrom Says:

    That’s why we use Alchemi… Great package.

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